Pedro Cruz

Research and Development Manager

Dr.Mohammed Mehdi Benmassaoud

Postdoctoral Associate

Breanna Runyon

Laboratory Technician III

Craig Meyers

Biological Scientist III

Dr.Bhaskar Birru

Postdoctoral Associate

Pedro Cruz’s scientific career focuses on the development of viral vectors (Ad, AAV, and HSV) for human gene therapy applications: gene promoter optimization (cell-restricted expression), capsid engineering (cell-specific targeting), and viral production utilizing cell lines. Over the past 24 years, Pedro has had the opportunity to supervise graduate and undergraduate students in the laboratory. It is always a pleasure to see the students learn to design their own plasmids in silico, construct actual plasmids at the bench, and create their own viruses for their theses. I have successfully mentored several University Scholars Program and Honor students in completing their theses. 

Achieving efficient transduction of resting microglia in vivo, for better or worse, has become his scientific obsession. Microglia play a major role in the homeostasis of the central nervous system. Achieving the genetic manipulation of microglia via viral gene therapy vectors will increase humanity's knowledge of brain function and may lead to the prevention/treatment of neurological diseases.

Dr. Mohammed Mehdi Benmassaoud, a.k.a Mehdi Benmassaoud, is a foreign post-doctoral associate from Morocco. He received his bachelor's in engineering management with a mechanical track from The College of New Jersey in 2016. During his time at TCNJ, Mehdi worked on different projects such as improving the efficacy of the electrode used for deep brain stimulation, which led to a conference paper, two conference posters, and exploring the potential negative impact of 5G on human health. In 2016, Mehdi Benmassaoud attended Rowan University to pursue his master’s degree in mechanical engineering. During his master’s, he worked under the supervision of Dr. Shivakumar I. Ranganathan to 3D print total knee arthroplasty loaded with antibiotics to reduce the potential post-infection rising issues. He was able to publish 2 manuscripts and attended a few conference posters. Receiving his Ph.D. in biomedical engineering in 2022, Mehdi worked under the supervision of Dr. Sebastian L. Vega to engineer biomaterials with diverse physical and chemical signaling to get different cellular responses. He specialized in the creation of hydrogel with spatial and temporal flexibility to induce different cell responses with the help of peptides. He was involved in 6 manuscripts as an author and attended several conferences. To further advance as a researcher, Mehdi joined the Andrews laboratory in September 2022 to develop an innovative microfluidic device that mimics the characteristics and properties of bone marrow. He wants to continue to improve his engineering skills through scaffold building as well as obtain more molecular biology skills like PCR, Western Blot, and seahorse assays. In October 2023, Mehdi moved with the Andrews laboratory from Temple University to the University of Florida. At UF, Mehdi is continuing his research in bone marrow microfluidic device formation and exploring the effect of HIV on hematopoietic stem cell differentiation.

Breanna Runyon is currently pursuing a Bachelor’s degree in Biology at Santa Fe College. She achieved her Associates of Arts at Eastern Gateway Community College in 2022. Working in tandem with her degree, her first job was a nutritional microbiology scientist with a focus on bacterial identification and culture growth. After completion of her A.A., she accepted a laboratory technician position in a R&D department at a cGMP facility where she learned the multifaceted applications of AAV therapies. While there, she specialized in cell culturing, bioreactor expansion, and large scale buffer/media production. After a year, she transitioned into a preclinical histology setting where she conducted experiments in support of gene therapy research. Using immunofluorescent and immunohistochemical techniques, she studied neurodegenerative diseases like Fredrich’s Ataxia and Alzheimer’s in the organelle of mice and primates. Breanna joined the Andrews Laboratory in May 2024 to assist in the study of HIV reservoirs through histology processing. She hopes to continue researching HIV and to expanding her skill set under her colleagues.

Dr. Bhaskar Birru is currently a Postdoctoral Associate in Dr. Andrews M Allision lab at Department of Pathology, Immunology, and Laboratory Medicine, University of Florida.  His focus on conducting novel research in tissue engineered brain microvasculature models, learning about a new disease (HIV infection and co morbid substance abuse), which involves innovative techniques (microfluidics, 3D bioprinting, image analysis). In his previous postdoctoral position, anti-inflammatory and antioxidant conjugate drug delivery systems, the development of 3D in vitro tympanic and round window membrane models, and microneedle-based drug delivery systems for the hearing loss management was carried out at University of Montana, USA.  He was graduated in Biotechnology from the highly reputed National Institute of Technology Warangal, India. His doctoral research was on the design and assessment of dynamic perfusion bioreactor for polymer guided bone regeneration.  

He undertook a sabbatical in the ‘Department of Materials science and Engineering’ at ‘The University of Sheffield’ with Newton-Bhabha Award. His keen interests in interdisciplinary areas of biomaterials and tissue engineering got him many applauds and awards including Junior Scientist Award from NAE, India and considered as best research article in Biomedical Journal, Elsevier.  He has authored 17 scientific publications in peer-reviewed international journals and 7 book chapters. His experience in research led him to pursue in bringing up a comprehensive, in-depth book on ‘Biomaterials in tissue engineering and regenerative medicine- published by Springer Nature’ to meet the aspirations of wide range of audience, including students, researchers and faculty in this core area.